Article

Unsupervised modeling of mutational landscapes of adeno-associated viruses viability

2023-10-27

Abstract excerpt

<h4>ABSTRACT</h4> Adeno-associated viruses 2 (AAV2) are minute viruses renowned for their capacity to infect human cells and akin organisms. They have recently emerged as prominent candidates in the field of gene therapy, primarily attributed to their inherent non-pathogenic nature in humans and the safety associated with their manipulation. The efficacy of AAV2 as gene therapy vectors hinges on their ability to...

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Literature Corpus work: 63688137-1ead-54b4-96a2-b375216f07b3
DOI: 10.1101/2023.10.26.564138

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