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Fabrication and delivery of mechano-actived microcapsules containing osteogenic factors in a large animal model of osteochondral injury

2021-09-24

Abstract excerpt

Chondral and osteochondral repair strategies are limited by adverse bony changes that occur after injury. Bone resorption can cause entire scaffolds, engineered tissues, or even endogenous repair tissues to subside below the cartilage surface. To address this translational issue, we fabricated poly(D,L-lactide-co-glycolide) (PLGA) microcapsules containing the pro-osteogenic agents triiodothyronine and ß-glyceropho...

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Literature Corpus work
6336d25e-ea2c-593b-9018-d82bd4cba65e
DOI
10.1101/2021.09.24.461696
Open publication

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Fabrication and delivery of mechano-actived microcapsules containing osteogenic factors in a large animal model of osteochondral injuryDOI 10.1101/2021.09.24.461696
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