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Injectable Nanoporous Microgels Generate Vascularized Constructs and Support Bone Regeneration in Critical-sized Defects

2021-11-05

Abstract excerpt

Large and aberrant bone fractures require ossification and concomitant vascularization for proper healing. Evidence indicates that osteogenesis and vessel growth are coupled in bone fractures. Although the synergistic role of endothelial cells has been recognized, vascularizing large bone grafts remains a challenge and has apprehended the clinical translation of engineered bone constructs. Here, we describe a faci...

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Literature Corpus work
d87ca57d-36dd-565f-aabf-d255763fe304
DOI
10.1101/2021.11.05.467366
Open publication

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