Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Viral and non-viral vectors for gene therapy in the treatment of bone-related disorders: molecular insights and clinical perspectives

29 Aug 2025

Abstract excerpt

Gene therapy offers a transformative approach for treating debilitating bone disorders by delivering therapeutic genetic material to target sites. The efficacy and safety of this approach are heavily reliant on the chosen delivery vehicle, either viral or non-viral vectors. Viral vectors are characterized by high transduction efficiency and the potential for long-term expression, as exemplified by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA Interference and Gene Delivery
Share to Viral Infections and Immunology Research
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40885057
DOI: 10.1016/j.mam.2025.101400

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Viral and non-viral vectors for gene therapy in the treatment of bone-related disorders: molecular insights and clinical perspectivesPMID 40885057Read ↗

Non-Viral Gene Delivery to Mesenchymal Stem Cells: Methods, Strategies and Application in Bone Tissue Engineering and RegenerationSemantic proximity Read ↗

Non-viral Gene Delivery Methods for Bone and JointsSemantic proximity Read ↗

Biomaterial‐based gene therapySemantic proximity Read ↗

Viral and non-viral vectors in gene therapy: current state and clinical perspectivesSemantic proximity Read ↗

Gene Therapy for Bone EngineeringSemantic proximity Read ↗

Lipid-based Non-viral Vector: Promising Approach for Gene DeliverySemantic proximity Read ↗

Non-Viral Delivery of Gene Therapy to the TendonSemantic proximity Read ↗

Non-viral gene delivery to human mesenchymal stem cells: a practical guide towards cell engineeringSemantic proximity Read ↗

Development of AAV-Mediated Gene Therapy Approaches to Treat Skeletal DiseasesSemantic proximity Read ↗

Gene Therapy in Orthopaedics: Progress and Challenges in Pre-Clinical Development and TranslationSemantic proximity Read ↗

Bone tissue engineering and repair by gene therapySemantic proximity Read ↗

Navigating the Hurdles of Intra-articular AAV Gene TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.