Article

Recapitulating bone development for tissue regeneration through engineered mesenchymal condensations and mechanical cues

2017-06-29

Abstract excerpt

<h4>ABSTRACT</h4> Large bone defects cannot heal without intervention and have high complication rates even with the best treatments available. In contrast, bone fractures naturally healing with high success rates by recapitulating the process of bone development through endochondral ossification. 1 Endochondral tissue engineering may represent a promising paradigm, but large bone defects are unable to naturally...

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Literature Corpus work: 5f55c323-9d28-5c96-ae95-d636e2e8ca6c
DOI: 10.1101/157362

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