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Ouro-seq: Improved Recovery of Full-Length circRNAs from Samples with Limited RNA Content

2026-08-14

Abstract excerpt

Circular RNAs (circRNAs) are an emerging class of RNAs with biomarker potential, but their detection in liquid biopsies is challenging due to low abundance. We developed Ouro-seq, a novel long-read sequencing protocol optimized for full-length circRNA recovery. Applied to urine, cervico-vaginal self-samples from cervical cancer patients, and plasma from lung cancer patients and controls, Ouro-seq recovered 2-5 tim...

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Literature Corpus work
e93419c2-0e84-5475-b812-42ba0e41eb43
DOI
10.64898/2026.08.14.744779
Open publication

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Ouro-seq: Improved Recovery of Full-Length circRNAs from Samples with Limited RNA ContentDOI 10.64898/2026.08.14.744779
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