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Unannotated small RNA clusters associated with circulating extracellular vesicles detect early stage liver cancer

28 Jul 2021

Abstract excerpt

OBJECTIVE: Surveillance tools for early cancer detection are suboptimal, including hepatocellular carcinoma (HCC), and biomarkers are urgently needed. Extracellular vesicles (EVs) have gained increasing scientific interest due to their involvement in tumour initiation and metastasis; however, most extracellular RNA (exRNA) blood-based biomarker studies are limited to annotated genomic regions. DESIGN: EVs were...

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PMID: 34321221
DOI: 10.1136/gutjnl-2021-325036

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