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Article

Circular RNA landscape in extracellular vesicles from human biofluids

31 Oct 2024

Abstract excerpt

BACKGROUND: Circular RNAs (circRNAs) have emerged as a prominent class of covalently closed single-stranded RNA molecules that exhibit tissue-specific expression and potential as biomarkers in extracellular vesicles (EVs) derived from liquid biopsies. Still, their characteristics and applications in EVs remain to be unveiled. METHODS: We performed a comprehensive analysis of EV-derived circRNAs (EV-circRNAs)...

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PMID: 39482783
DOI: 10.1186/s13073-024-01400-w

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