Back to search

Article

NAD kinase promotes <i>Staphylococcus aureus</i> pathogenesis by supporting production of virulence factors and protective enzymes

2021-08-09

Abstract excerpt

Nicotinamide adenine dinucleotide phosphate (NADPH) is the primary electron donor for reductive reactions that are essential for the biosynthesis of major cell components in all organisms. Nicotinamide adenine dinucleotide kinase (NADK) is the only enzyme that catalyzes synthesis of NADP(H) from NAD(H). While the enzymatic properties and physiological functions of NADK have been thoroughly studied, the role of NAD...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
62a51c53-4c01-56bd-8a59-a5fbe5d5b941
DOI
10.1101/2021.08.09.455706
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
NAD kinase promotes <i>Staphylococcus aureus</i> pathogenesis by supporting production of virulence factors and protective enzymesDOI 10.1101/2021.08.09.455706
NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymesSemantic proximity
NAD+-targeting by bacteria: an emerging weapon in pathogenesisSemantic proximity
A Nitric Oxide–Inducible Lactate Dehydrogenase Enables <i>Staphylococcus aureus</i> to Resist Innate ImmunitySemantic proximity
Metabolic reprogramming promotes <i>Staphylococcus aureus</i> serum resistance during bacteraemiaSemantic proximity
Large-scale CRISPRi and transcriptomics of <i>Staphylococcus epidermidis</i> identify genetic factors implicated in commensal-pathogen lifestyle versatilitySemantic proximity
The 5’-NAD cap of RNAIII modulates toxin production in <i>Staphylococcus aureus</i> isolatesSemantic proximity
NAD <sup>+</sup> metabolism is a key modulator of bacterial respiratory epithelial infectionsSemantic proximity
Metabolic reprogramming promotes Staphylococcus aureus serum resistance.Semantic proximity
<i>Staphylococcus aureus</i> targets the purine salvage pathway to kill phagocytesSemantic proximity
Host nutrient milieu drives an essential role for aspartate biosynthesis during invasive <i>Staphylococcus aureus</i> infectionSemantic proximity
Regulatory Requirements for Staphylococcus aureus Nitric Oxide Resistance.Semantic proximity
Large-scale CRISPRi and transcriptomics of Staphylococcus epidermidis identify genetic factors implicated in commensal-pathogen lifestyle versatilitySemantic proximity
Select a neighboring publication to make it the new centre.