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Metabolic reprogramming promotes <i>Staphylococcus aureus</i> serum resistance during bacteraemia

2026-01-14

Abstract excerpt

<h4>ABSTRACT</h4> Staphylococcus aureus is a leading cause of bloodstream infections causing an estimated 300,000 deaths worldwide. Using a functional genomics approach, our group previously identified that adaptation of S. aureus to human serum is polygenic, with a clinically occurring non-synonymous mutation (V76I) in dihydrolipoamide dehydrogenase ( lpdA1 / pdhD ) improving bacterial survival. In this work...

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Literature Corpus work
500656b1-9cf4-5d5f-b910-46d772376994
DOI
10.64898/2026.01.14.699454
Open publication

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Metabolic reprogramming promotes <i>Staphylococcus aureus</i> serum resistance during bacteraemiaDOI 10.64898/2026.01.14.699454
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