Host nutrient milieu drives an essential role for aspartate biosynthesis during invasive <i>Staphylococcus aureus</i> infection

Abstract excerpt

Significance Staphylococcus aureus can infect a diverse array of host environments. The broad tissue tropism of S. aureus requires metabolic flexibility to utilize the variety of nutrient sources found within target organ systems. In this work, we conducted a systematic analysis of the central metabolic pathways required for S. aureus survival during bone infection, one of the most frequent sites of invasive...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antimicrobial Resistance in Staphylococcus
• Share to Infective Endocarditis Diagnosis and Management
• Share to Orthopedic Infections and Treatments