Article

Germline MET pathogenic variants in papillary renal cell carcinomas type I: specific phenotype in French population and novel germline pathogenic variant MET c.3389T>C, p.(Leu1130Ser)

2021-06-02

Abstract excerpt

Hereditary papillary renal cell carcinoma (HPRCC) is a rare inherited renal cancer syndrome characterized by bilateral and multifocal papillary type 1 renal tumors (PRCC1). Activating germline pathogenic variants of MET gene were identified in HPRCC families. We reviewed the medical and molecular records of a large French series of 158 patients screened for MET oncogenic variants (153 index-cases and five relati...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 625f603e-ae8c-5c44-9e6a-2b999fed9d57
DOI: 10.22541/au.162263710.06329757/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Germline MET pathogenic variants in papillary renal cell carcinomas type I: specific phenotype in French population and novel germline pathogenic variant MET c.3389T>C, p.(Leu1130Ser)DOI 10.22541/au.162263710.06329757/v1Read

Novel germline MET pathogenic variants in French patients with papillary renal cell carcinomas type I.Semantic proximity Read

Germline and somatic c-met mutations in multifocal/bilateral and sporadic papillary renal carcinomas of selected patients.Semantic proximity Read

Hereditary papillary renal cell carcinomaSemantic proximity Read

EARLY ONSET HEREDITARY PAPILLARY RENAL CARCINOMA: GERMLINE MISSENSE MUTATIONS IN THE TYROSINE KINASE DOMAIN OF THE MET PROTO-ONCOGENESemantic proximity Read

Various Histological Types of Renal Cell Carcinoma Associated With Hereditary Papillary Renal Cell Carcinoma (HPRCC): a Case ReportSemantic proximity Read

Novel mutation in the ATP-binding site of theMET oncogene tyrosine kinase in a HPRCC familySemantic proximity Read

Two North American families with hereditary papillary renal carcinoma and identical novel mutations in the MET proto-oncogene.Semantic proximity Read

Hereditary and sporadic papillary renal carcinomas with c-met mutations share a distinct morphological phenotype.Semantic proximity Read

Hereditary papillary renal carcinoma type I.Semantic proximity Read

Clear cell and papillary renal cell carcinomas in hereditary papillary renal cell carcinoma (HPRCC) syndrome: a case report.Semantic proximity Read

Papillary renal cell carcinoma: analysis of germline mutations in the MET proto-oncogene in a clinic-based population.Semantic proximity Read

MET alterations in biphasic squamoid alveolar papillary renal cell carcinomas and clinicopathological features.Semantic proximity Read