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Article

Hereditary and sporadic papillary renal carcinomas with c-met mutations share a distinct morphological phenotype.

The American journal of pathology - 1 Aug 1999

Lubensky I A, Schmidt L, Zhuang Z, Weirich G, Pack S, Zambrano N, Walther M M, Choyke P, Linehan W M, Zbar B

Abstract excerpt

Germline mutations of c-met oncogene at 7q31 have been detected in patients with hereditary papillary renal cell carcinoma. In addition, c-met mutations were shown to play a role in 13% of patients with papillary renal cell carcinoma and no family history of renal tumors. The histopathology of papillary renal cell carcinoma with c-met mutations has not been previously described. We analyzed the histopathology of...

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Identifiers

PMID: 10433944
DOI: 10.1016/S0002-9440(10)65147-4
PMCID: PMC1866853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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