Article
MET alterations in biphasic squamoid alveolar papillary renal cell carcinomas and clinicopathological features.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Mar 2021
Denize Thomas, Just Pierre Alexandre, Sibony Mathilde, Blons Hélène, Timsit Marc Olivier, Drossart Tom, Jakubowicz Deborah, Broudin Chloé, Morini Aurélien, Molina Thierry, Vano Yann, Auvray-Kuentz Marie, Richard Stéphane, Mejean Arnaud, Gimenez Roqueplo Anne Paule, Burnichon Nelly, Verkarre Virginie
Abstract excerpt
Biphasic squamoid alveolar papillary renal cell carcinoma (BSA-PRCC) is a recently studied lesion considered a morphologic variant of papillary renal cell carcinoma (RCC), more closely related to type 1. Considering the role of proto-oncogene MET in both sporadic type 1 papillary RCC and hereditary papillary RCC, we aimed to explore the role of MET activation in the oncogenesis of BSA-PRCC. We identified 17...
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