Article

ABI1 regulates transcriptional activity of Androgen Receptor by novel DNA and AR binding mechanism

2023-05-26

Abstract excerpt

<h4>ABSTRACT</h4> Transcription regulates key functions of living organisms in normal and disease states, including cell growth and development, embryonic and adult tissue organization, and tumor progression. Here we identify a novel mechanism of transcriptional regulation by an actin regulatory and signaling protein, Abelson Interactor 1 (ABI1). Using prostate cancer models, we uncover a reciprocal regulation be...

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Identifiers and source

Literature Corpus work: 62285366-5a2c-5c53-a4d3-5c72fcf2e5a3
DOI: 10.1101/2023.05.26.542350

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