Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic rewiring of the androgen receptor protein interaction network correlates with prostate cancer clinical outcomes.

Integrative biology : quantitative biosciences from nano to macro - 1 Oct 2011

Paliouras Miltiadis, Zaman Naif, Lumbroso Rose, Kapogeorgakis Laurie, Beitel Lenore K, Wang Edwin, Trifiro Mark

Abstract excerpt

The androgen receptor (AR) is a ligand-inducible transcription factor, a member of the nuclear receptor superfamily, which plays an important role in the development and progression of prostate cancer (CaP). The transformation to CaP has been linked to several somatic AR gene mutations and changes in AR protein complex formation, which in turn increase the potential activity of the receptor. Thus, to address the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorocebus aethiops
Share to Chromatography, Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to COS Cells

Share to Protein Interaction Maps

Share to Proteomics

Share to Receptors, Androgen

Share to Systems Biology

Share to Tandem Mass Spectrometry

Source

Identifiers

PMID: 21901193
DOI: 10.1039/c1ib00038a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic rewiring of the androgen receptor protein interaction network correlates with prostate cancer clinical outcomes.PMID 21901193Read ↗

Proteomic Landscape of Prostate Cancer: The View Provided by Quantitative Proteomics, Integrative Analyses, and Protein InteractomesSemantic proximity Read ↗

Analyzing the Androgen Receptor Interactome in Prostate Cancer: Implications for Therapeutic InterventionSemantic proximity Read ↗

Molecular pathogenesis and progression of prostate cancer.Semantic proximity Read ↗

Research Resource: Androgen Receptor Activity Is Regulated Through the Mobilization of Cell Surface Receptor Networks.Semantic proximity Read ↗

Androgen Receptor Signaling Regulates the Transcriptome of Prostate Cancer Cells by Modulating Global Alternative SplicingSemantic proximity Read ↗

Comparative RNA-seq analysis reveals potential mechanisms mediating the conversion to androgen independence in an LNCaP progression cell model.Semantic proximity Read ↗

Patient-matched analysis identifies deregulated networks in prostate cancer to guide personalized therapeutic interventionSemantic proximity Read ↗

Androgen receptor signaling regulates the transcriptome of prostate cancer cells by modulating global alternative splicingSemantic proximity Read ↗

Evidence for the Presence of Disease-Perturbed Networks in Prostate Cancer Cells by Genomic and Proteomic Analyses: A Systems Approach to DiseaseSemantic proximity Read ↗

Adaptive responses of androgen receptor signaling in castration-resistant prostate cancer.Semantic proximity Read ↗

Oncogenic activation in prostate cancer progression and metastasis: Molecular insights and future challengesSemantic proximity Read ↗

Androgen signaling and its interactions with other signaling pathways in prostate cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.