Article
Androgen receptor (AR) coregulators: an overview.
Endocrine reviews - 1 Apr 2002
Heinlein Cynthia A, Chang Chawnshang
Abstract excerpt
The biological action of androgens is mediated through the androgen receptor (AR). Androgen-bound AR functions as a transcription factor to regulate genes involved in an array of physiological processes, most notably male sexual differentiation and maturation, and the maintenance of spermatogenesis. The transcriptional activity of AR is affected by coregulators that influence a number of functional properties of...
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