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The Role of cccDNA in HBV Maintenance

21 Jun 2017

Abstract excerpt

Chronic hepatitis B virus (HBV) infection continues to be a major health burden worldwide; it can cause various degrees of liver damage and is strongly associated with the development of liver cirrhosis and hepatocellular carcinoma. The molecular mechanisms determining HBV persistence are not fully understood, but these appear to be multifactorial and the unique replication strategy employed by HBV enables its...

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PMID: 28635668
DOI: 10.3390/v9060156

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