Article
Colorectal adenosquamous carcinoma: genomic profiling of a rare histotype of colorectal cancer.
Virchows Archiv : an international journal of pathology - 1 May 2023
Angerilli Valentina, Parente Paola, Businello Gianluca, Vanoli Alessandro, Paudice Michele, Perrone Giovanni, Munari Giada, Govoni Ilaria, Neri Giuseppe, Rebellato Elena, Parrella Paola, Grillo Federica, Mastracci Luca, Fassan Matteo
Abstract excerpt
Colorectal adenosquamous carcinoma (ASC) is exceedingly rare, comprising less than 0.1% of all colorectal malignancies, and is characterized by an aggressive disease course, with a higher metastatic rate and worse outcome than conventional colorectal adenocarcinoma. A comprehensive molecular profile of this group of neoplasms is still lacking. A total of 22 cases of colorectal ASCs (with 22 primary lesions and 7...
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