Article

Liver transplant-facilitated recovery of MAIT cell from dysregulation in HBV-related liver failure demonstrates clinical benefits

2024-02-07

Abstract excerpt

<title>Abstract</title> <p>Mucosal-associated invariant T (MAIT) cells exert multifaceted effects such as anti-microbial activity, tissue repair, and pro-fibrotic effects across various disease settings. Nonetheless, their role in liver injury and hemostasis is a current topic of debate. Here, we presented a MAIT cell-centered profiling in chronic HBV-infected patients with varying degree of liver injury and thos...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3d20b704-a694-57cf-8f7e-57d91e46a3a7
DOI: 10.21203/rs.3.rs-3875745/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Liver transplant-facilitated recovery of MAIT cell from dysregulation in HBV-related liver failure demonstrates clinical benefitsDOI 10.21203/rs.3.rs-3875745/v1Read

Single-cell analysis reveals a pathogenic cellular module associated with early allograft dysfunction after liver transplantationSemantic proximity Read

Tissue-resident memory T cells in chronic liver diseases: Phenotype, development and function.Semantic proximity Read

Biliary epithelium and liver B cells exposed to bacteria activate intrahepatic MAIT cells through MR1Semantic proximity Read

Single cell RNA-sequencing delineates CD8 + tissue resident memory T cells maintaining rejection in liver transplantationSemantic proximity Read

Mucosal associated invariant T cells are differentially impaired in tolerant and immunosuppressed liver transplant recipients.Semantic proximity Read

The human liver microenvironment shapes the homing and function of CD4 <sup>+</sup> T-cell populationsSemantic proximity Read

Single-cell multimodal analysis reveals the dynamic immunopathogenesis of HBV-ACLF progressionSemantic proximity Read

TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functionsSemantic proximity Read

Single cell profiling of functionally cured Chronic Hepatitis B patients reveals the emergence of activated innate and an altered adaptive immune response in the intra-hepatic environmentSemantic proximity Read

Uncovering the Single-cell Transcriptomic Signatures and Pathogenesis of Mucosal-associated Invariant T cells during Nonalcoholic SteatohepatitisSemantic proximity Read

IL-2high tissue-resident T cells in the human liver: Sentinels for hepatotropic infection.Semantic proximity Read

Mucosal-Associated Invariant T Cells in Chronic Inflammatory Liver Disease.Semantic proximity Read