Article
High‐throughput T‐cell receptor sequencing across chronic liver diseases reveals distinct disease‐associated repertoires
7 Aug 2015
Abstract excerpt
UNLABELLED: Hepatic T-cell infiltrates and a strong genetic human leukocyte antigen association represent characteristic features of various immune-mediated liver diseases. Conceptually the presence of disease-associated antigens is predicted to be reflected in T-cell receptor (TCR) repertoires. Here, we aimed to determine if disease-associated TCRs could be identified in the nonviral chronic liver diseases...
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