Unravelling the Molecular Pathways of Feline Diffuse Iris Melanoma Progression

Abstract excerpt

<title>Abstract</title> <p>Feline diffuse iris melanoma (FDIM) is the most common primary ocular tumour in cats, with high metastatic potential. Greater intraocular invasion correlates with increased mortality. No effective therapeutics exist for metastatic disease, partly due to a lack of known molecular targets associated with aggressive tumour behaviour. Here, we define the transcriptomic landscape of FDIM in...

Topics

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• Cat Diseases
• Cats
• Eye Neoplasms
• Gene Expression Profiling
• Gene Expression Regulation, Neoplastic
• Melanoma
• Mutation
• Real-Time Polymerase Chain Reaction

Identifiers and source

Literature Corpus work

619dfe72-6091-5c27-ab54-a40c731d76bf

DOI

10.21203/rs.3.rs-6228571/v1