Article

Somatic inactivating <i>PTPRJ</i> mutations and dysregulated pathways identified in canine melanoma by integrated comparative genomic analysis

2017-09-30

Abstract excerpt

<h4>ABSTRACT</h4> Canine malignant melanoma, a significant cause of mortality in domestic dogs, is a powerful comparative model for human melanoma, but little is known about its genetic etiology. We mapped the genomic landscape of canine melanoma through multi-platform analysis of 37 tumors (31 mucosal, 3 acral, 2 cutaneous, and 1 uveal) and 17 matching constitutional samples including long- and short-insert whol...

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Literature Corpus work: ff83282b-2272-53f8-9295-aff1612d5caa
DOI: 10.1101/196337

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