Article

Lymph-node transcriptomics define prognostic immune states in mucosal melanoma and reveal IBA1 as a practical biomarker for improved prognosis

2025-09-21

Abstract excerpt

Mucosal melanoma (MM) is a rare and aggressive cancer in humans with poor prognosis and limited response to immunotherapy or targeted therapy. Progress has been hindered by the lack of immune-competent, translational models. Dogs develop oral mucosal melanoma (OMM), a biologically equivalent disease, making them a valuable companion animal model that shares the human environment and immune context. In this study,...

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Literature Corpus work: 5ce897b8-f487-5d90-ada0-28678c39f802
DOI: 10.1101/2025.09.20.677500

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