Article

Genetic liability to meniscus degeneration and its comorbidity patterns: a phenome-wide association study in the UK Biobank

2025-09-25

Abstract excerpt

Meniscus degeneration is a common knee pathology causing pain, disability, and osteoarthritis. While mechanical factors are established, the contribution of inherited genetic liability to its systemic disease patterns remains unclear. We applied a polygenic risk score (PRS) for meniscus degeneration, derived from FinnGen genome-wide association study (GWAS) results to 323,999 UK Biobank participants and conducted...

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Literature Corpus work: 619b8103-1e3f-573a-a7a3-ea3da16d5a2d
DOI: 10.1101/2025.09.23.25336468

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