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Article

Osteoarthritis phenotypes: advancing precision medicine through clinical, structural, and molecular stratification.

International orthopaedics - 1 Jun 2026

Vaishya Raju, Wamuyu Evans Ngugi, Vaish Abhishek, Handa Rohini, Kumar Dhavendra

Abstract excerpt

PURPOSE: Osteoarthritis (OA) is now understood as a heterogeneous syndrome driven by diverse biological, biomechanical, metabolic, genetic, and molecular mechanisms. This variability explains differences in disease progression and treatment response, challenging the traditional "one-size-fits-all" approach. This review highlights OA phenotyping as a key step toward precision medicine, focusing on clinical,...

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PMID: 42141125
DOI: 10.1007/s00264-026-06845-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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