Article

Identifying genetic variants and pathways associated with extreme levels of fetal hemoglobin in Sickle Cell Disease in Tanzania.

2020-05-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Sickle cell disease (SCD) is a blood disorder caused by a point mutation on the beta globin gene resulting in the synthesis of abnormal hemoglobin. Fetal hemoglobin (HbF) reduces disease severity, but the levels vary from one individual to another. Most research has focused on common variants which differ across populations and hence do not fully account for HbF...

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Literature Corpus work: 612ab612-4f94-53c5-9b68-55e114fae723
DOI: 10.21203/rs.2.22041/v3

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