Article

Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis

2019-12-03

Abstract excerpt

<h4>Objectives</h4> Synovial fibroblasts (SFs) produce a variety of pathogenic molecules in the inflamed synovium of rheumatoid arthritis (RA). We aimed to gain insight into the pathogenic mechanisms of SFs through elucidating the genetic contribution to molecular regulatory networks under inflammatory condition. <h4>Methods</h4> SFs from RA and osteoarthritis (OA) patients (n=30 each) were stimulated with 8 dif...

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Literature Corpus work: 61261629-5e7f-5375-b37e-c5b164a60538
DOI: 10.1101/861781

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