Article

Gene-regulatory network study of rheumatoid arthritis in single-cell chromatin landscapes of peripheral blood mononuclear cells

2021-09-17

Abstract excerpt

Rheumatoid arthritis is a chronic autoinflammatory disease with an elusive etiology. Assays for transposase-accessible chromatin with single-cell sequencing (scATAC-seq) contribute to the progress in epigenetic studies. However, the impact of epigenetic technology on autoimmune diseases has not been objectively analyzed. Therefore, scATAC-seq was performed to generate a high-resolution map of accessible loci in pe...

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Literature Corpus work: ccfe57d8-bba2-5dc4-ba4a-a59597adad2c
DOI: 10.21203/rs.3.rs-899470/v1

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