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Article

Multiomics landscape of synovial fibroblasts in rheumatoid arthritis

1 Mar 2021

Abstract excerpt

BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune disease characterized by tumor-like hyperplasia and inflammation of the synovium, which causes synovial cell invasion into the bone and cartilage. In RA pathogenesis, various molecules in effector cells (i.e., immune cells and mesenchymal cells) are dysregulated by genetic and environmental factors. Synovial fibroblasts (SFs), the most abundant resident...

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PMID: 33641680
DOI: 10.1186/s41232-021-00157-8

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