Article

Integration of scRNA-Seq and Bulk RNA-Seq Reveals Molecular Characterization of the Immune Microenvironment in Rheumatoid Arthritis

2025-02-19

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic, symmetrical, aggressive autoimmune disease involving multiple body joints. This study calculated the proportions of cell clusters, and 657 DEGs in CD16+ monocyte clusters were identified according to proportion and immune score. The interaction intensity of CD8+T cell clusters in RA was elevated, with strong interaction. The output signals of platelets, monocytes, and NK cel...

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Literature Corpus work: 1277d3a3-3df0-5f93-ba87-b6df25881882
DOI: 10.22541/au.173996147.79705722/v1

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