Article

Multi-lineage transcriptional and cell communication signatures define pathways in individuals at-risk for developing rheumatoid arthritis that initiate and perpetuate disease

2025-03-31

Abstract excerpt

<title>Abstract</title> <p>Elevated anti-citrullinated protein antibodies (ACPA) levels in the peripheral blood are associated with an increased risk for developing rheumatoid arthritis (RA). Currently, no treatments are available that prevent progression to RA in these at-risk individuals. In addition, diverse pathogenic mechanisms underlying a common clinical phenotype in RA complicate therapy as no single agen...

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Literature Corpus work: 20f48650-7107-5b5d-85f7-1245c89acddb
DOI: 10.21203/rs.3.rs-6165802/v1

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