Article

The hidden intricacies of aquaporins: Remarkable details in a common structural scaffold

2022-03-29

Abstract excerpt

Evolution turned aquaporins (AQPs) into the most efficient facilitators of passive water flow through cell membranes at no expense of solute discrimination. In spite of a plethora of solved AQP structures, many structural details remain hidden. Here, by combining extensive sequence- and structural-based analysis of a unique set of 20 non-redundant high-resolution structures and molecular dynamics simulations of 4...

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Identifiers and source

Literature Corpus work: 60e3001c-b29e-54bf-a056-7b3147b229cb
DOI: 10.1101/2022.03.28.486021

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