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Article

The aquaporin family of water channels in kidney.

Kidney international - 1 Oct 1995

Nielsen S, Agre P

Abstract excerpt

The longstanding puzzle of membrane water permeability was advanced by the discovery of channel-forming integral protein (CHIP). This protein was shown to function as a water channel when expressed in Xenopus oocytes or when reconstituted into synthetic membranes. Site-directed mutagenesis and electron crystallography reveal tetrameric organization of CHIP, and the two halves of CHIP are tandem repeats folded...

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Source

Identifiers

PMID: 8569067
DOI: 10.1038/ki.1995.389

Genes

AQP2
AQP1
AQP3
AQP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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