Article
Electrostatics of aquaporin and aquaglyceroporin channels correlates with their transport selectivity.
Proceedings of the National Academy of Sciences of the United States of America - 2 Mar 2010
Oliva Romina, Calamita Giuseppe, Thornton Janet M, Pellegrini-Calace Marialuisa
Abstract excerpt
Aquaporins are homotetrameric channel proteins, which allow the diffusion of water and small solutes across biological membranes. According to their transport function, aquaporins can be divided into "orthodox aquaporins", which allow the flux of water molecules only, and "aquaglyceroporins", which facilitate the diffusion of glycerol and other small solutes in addition to water. The contribution of individual...
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