Article
Control of the selectivity of the aquaporin water channel family by global orientational tuning.
Science (New York, N.Y.) - 19 Apr 2002
Tajkhorshid Emad, Nollert Peter, Jensen Morten Ø, Miercke Larry J W, O'Connell Joseph, Stroud Robert M, Schulten Klaus
Abstract excerpt
Aquaporins are transmembrane channels found in cell membranes of all life forms. We examine their apparently paradoxical property, facilitation of efficient permeation of water while excluding protons, which is of critical importance to preserving the electrochemical potential across the cell mem...
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