Article

HIV-1 Rev interacts with HERV-K RcREs present in the human genome and promotes export of unspliced HERV-K proviral RNA

2019-11-03

Abstract excerpt

<h4>Background</h4> The HERV-K (HML-2) viruses are the youngest of the human endogenous retroviruses. They are present as several almost complete proviral copies and numerous fragments in the human genome. Many HERV-K proviruses express a regulatory protein Rec, which binds to an element present in HERV-K mRNAs called the RcRE. This interaction is necessary for the nucleo-cytoplasmic export and expression of HERV...

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Literature Corpus work: 60d746f5-437c-5f58-9dc1-7abeaa083e70
DOI: 10.1101/822619

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