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Article

Targeting endogenous retrovirus gene transcription in human cancers

2018-10-24

Abstract excerpt

Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections that make up to 8% of the human genome. Although these elements are mostly fragmented and inactive, many proviruses belonging to the HERV-K (HML-2) family, the only lineage still proliferating in the genome after the human-chimpanzee split, have intact open reading frames, some encoding for accessory genes called np9 and rec that intera...

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Literature Corpus work
069586ed-6b96-588b-8bb0-7de5ebe56e17
DOI
10.1101/449686
Open publication

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Targeting endogenous retrovirus gene transcription in human cancersDOI 10.1101/449686
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