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Article

HERV-K(HML-2) rec and np9 transcripts not restricted to disease but present in many normal human tissues

4 Mar 2015

Abstract excerpt

BACKGROUND: Human endogenous retroviruses of the HERV-K(HML-2) group have been associated with the development of tumor diseases. Various HERV-K(HML-2) loci encode retrovirus-like proteins, and expression of such proteins is upregulated in certain tumor types. HERV-K(HML-2)-encoded Rec and Np9 proteins interact with functionally important cellular proteins and may contribute to tumor development. Though, the...

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PMID: 25750667
DOI: 10.1186/s13100-015-0035-7

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