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Article

Tfap2a is a novel gatekeeper of differentiation in renal progenitors during kidney development

2018-11-02

Abstract excerpt

Renal functional units known as nephrons undergo patterning events during development that create a segmental array of cellular populations with discrete physiological tasks. Knowledge about the terminal differentiation programs of each nephron segment has central importance for understanding kidney disease and to advance regenerative medicine, as mammalian nephrons grown in organoid cultures from pluripotent cell...

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Literature Corpus work
60d38694-73a0-51bc-8b67-da0decd6f9ef
DOI
10.1101/460105
Open publication

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Tfap2a is a novel gatekeeper of differentiation in renal progenitors during kidney developmentDOI 10.1101/460105
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