Article
Tfap2a is a novel gatekeeper of nephron differentiation during kidney development
1 Jan 2019
Abstract excerpt
Renal functional units known as nephrons undergo patterning events during development that create a segmental array of cellular compartments with discrete physiological identities. Here, from a forward genetic screen using zebrafish we report the discovery that transcription factor AP-2 alpha (tfap2a) coordinates a gene regulatory network that activates the terminal differentiation program of distal segments in...
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