Article
Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
Developmental cell - 22 May 2017
Naiman Natalie, Fujioka Kaoru, Fujino Mari, Valerius M Todd, Potter S Steven, McMahon Andrew P, Kobayashi Akio
Abstract excerpt
The kidney contains the functional units, the nephrons, surrounded by the renal interstitium. Previously we discovered that, once Six2-expressing nephron progenitor cells and Foxd1-expressing renal interstitial progenitor cells form at the onset of kidney development, descendant cells from these populations contribute exclusively to the main body of nephrons and renal interstitial tissues, respectively,...
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