Article

A single-cell multi-omic and spatial atlas of B-cell lymphomas reveals differentiation drives intratumor heterogeneity

2023-11-07

Abstract excerpt

Intratumor heterogeneity underpins cancer pathogenesis and evolution, although it is typically considered independent from the differentiation processes that drive physiological cell-type diversity. As cancer types and subtypes arise from different cell types, we investigated whether cellular differentiation influences intratumor heterogeneity. Nodal B-cell non-Hodgkin lymphomas are a diverse set of cancers origin...

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Literature Corpus work: 8463b9a9-4832-5364-b10c-bed71af24c6e
DOI: 10.1101/2023.11.06.565756

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