Article

Taking rapid and intermittent cocaine infusions enhances both incentive motivation for the drug and cocaine-induced gene regulation in corticostriatal regions

2020-04-24

Abstract excerpt

<h4>ABSTRACT</h4> A goal in addiction research is to distinguish forms of neuroplasticity that are involved in the transition to addiction from those involved in mere drug taking. Animal models of drug self-administration are essential in this context. Here, we compared in male rats two cocaine self-administration procedures that differ in the extent to which they evoke addiction-like behaviours. We measured both...

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Literature Corpus work: 6060c7b5-9b7e-503e-95e4-656be45bc0ee
DOI: 10.1101/2020.04.22.055715

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