Article

Establishment of Multi-stage Intravenous Self-administration Paradigms in Mice

2020-11-27

Abstract excerpt

<h4>ABSTRACT</h4> A genetically tractable animal model would provide a needed strategy to resolve the biological basis of drug addiction. Intravenous self-administration (IVSA) is the gold standard for modeling cocaine and opioid addiction in animals, but technical limitations have precluded the widespread use of IVSA in mice. Here, we describe the first IVSA paradigms for mice that capture the multi-stage nature...

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Literature Corpus work: 7baf26d4-4bd8-547f-99ba-0805d78d075d
DOI: 10.1101/2020.11.25.398503

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