Article

Avoidance of MAIT cells is an essential determinant of <i>Listeria monocytogenes</i> pathogenesis

2025-10-14

Abstract excerpt

Mucosal-associated invariant T (MAIT) cells are among the most conserved and abundant innate-like T cells in humans that recognize microbial-derived riboflavin precursors and elicit potent antimicrobial responses. The foodborne pathogen Listeria monocytogenes is a broad host-range facultative intracellular pathogen that lacks the riboflavin biosynthetic pathway, leading us to hypothesize that this deficiency is p...

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Literature Corpus work: 605517ef-b279-51ea-a8f9-6e0842359c2c
DOI: 10.1101/2025.10.13.682223

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