Human MAIT-cell responses to <i>Escherichia coli</i>: activation, cytokine production, proliferation, and cytotoxicity

Abstract excerpt

Mucosa-associated invariant T cells are a large and relatively recently described innate-like antimicrobial T-cell subset in humans. These cells recognize riboflavin metabolites from a range of microbes presented by evolutionarily conserved major histocompatibility complex, class I-related molecules. Given the innate-like characteristics of mucosa-associated invariant T cells and the novel type of antigens they...

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