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Th2 Cells in Health and Disease

2 Dec 2016

Abstract excerpt

Helper T (Th) cell subsets direct immune responses by producing signature cytokines. Th2 cells produce IL-4, IL-5, and IL-13, which are important in humoral immunity and protection from helminth infection and are central to the pathogenesis of many allergic inflammatory diseases. Molecular analysis of Th2 cell differentiation and maintenance of function has led to recent discoveries that have refined our...

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PMID: 27912316
DOI: 10.1146/annurev-immunol-051116-052350

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