Article

Pathogen and human NDPK-proteins promote AML cell survival via monocyte NLRP3-inflammasome activation

2023-01-03

Abstract excerpt

A history of infection has been linked with increased risk of acute myeloid leukaemia (AML) and related myelodysplastic syndromes (MDS). Furthermore, AML and MDS patients suffer frequent infections because of disease-related impaired immunity. However, the role of infections in the development and progression of AML and MDS remains poorly understood. We and others previously demonstrated that the human nucleoside...

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Literature Corpus work: 601cb28c-74bf-58b5-8a80-80fa0ecd7783
DOI: 10.1101/2023.01.02.522534

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