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Cell-free DNA in plasma as an essential immune system regulator

15 Oct 2020

Abstract excerpt

The cell-free DNA (cfDNA) is always present in plasma, and it is biomarker of growing interest in prenatal diagnostics as well as in oncology and transplantology for therapy efficiency monitoring. But does this cfDNA have a physiological role? Here we show that cfDNA presence and clearance in plasma of healthy individuals plays an indispensable role in immune system regulation. We exposed THP1 cells to healthy...

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PMID: 33060738
DOI: 10.1038/s41598-020-74288-2

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